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Writer's pictureClaire Jarvis

Nutrigenomics and Migraines: Personalised Nutrition for Migraine and Vestibular Migraine Management

Updated: Nov 24

Migraines, including vestibular migraines, are complex neurological conditions influenced by a variety of factors, including genetics. While traditional approaches to managing migraines often focus on symptom relief, emerging research into nutrigenomics offers a personalised, root-cause-focused approach to reducing migraine frequency and severity. Nutrigenomics, the study of how genes interact with diet and lifestyle, provides unique insights into how your individual genetic makeup may contribute to migraines and how targeted nutrition can help manage them.


As a naturopathic nutritional therapist, I use nutrigenomics to help clients uncover genetic susceptibilities that may be driving their migraines. By understanding these genetic influences, we can develop a tailored plan to optimise your health and reduce your symptoms.



Nutrigenomics and Migraines: Personalised Nutrition for Migraine and Vestibular Migraine Management

Migraines, including vestibular migraines, are complex neurological conditions influenced by a variety of factors, including genetics. While traditional approaches to managing migraines often focus on symptom relief, emerging research into nutrigenomics offers a personalised, root-cause-focused approach to reducing migraine frequency and severity. Nutrigenomics, the study of how genes interact with diet and lifestyle, provides unique insights into how your individual genetic makeup may contribute to migraines and how targeted nutrition can help manage them.

As a naturopathic nutritional therapist, I use nutrigenomics to help clients uncover genetic susceptibilities that may be driving their migraines. By understanding these genetic influences, we can develop a tailored plan to optimise your health and reduce your symptoms.


What is Nutrigenomics?

Nutrigenomics examines the relationship between your genes, diet, and overall health. Our genes play a critical role in how the body processes nutrients, produces energy, and manages inflammation—all factors that influence migraine triggers and severity. While you can’t change your genetic code, you can modify how your genes are expressed through targeted dietary and lifestyle changes.


How Nutrigenomics Relates to Migraine and Vestibular Migraine Management

Certain genetic variations, also known as single nucleotide polymorphisms (SNPs), can predispose individuals to migraines by influencing key processes in the body. Nutrigenomics helps us identify these variations and implement strategies to mitigate their effects.


Common Genetic Factors in Migraines:

  1. MTHFR Gene Variants:

    • The MTHFR gene affects the body’s ability to metabolise folate, an essential nutrient for detoxification and neurotransmitter production. Variants in this gene may lead to increased homocysteine levels, which are associated with migraines.

    • Nutritional support: Optimising folate intake through methylated forms (e.g., methylfolate) and addressing other B vitamins, like B6 and B12, can support proper methylation.

  2. COMT Gene Variants:

    • The COMT gene influences how the body breaks down stress hormones like adrenaline and dopamine. Variations in this gene may lead to heightened sensitivity to stress, a common migraine trigger.

    • Nutritional support: Magnesium, omega-3 fatty acids, and stress-reducing techniques can help modulate this pathway.

  3. CYP450 Gene Variants:

    • The CYP450 gene family affects the detoxification of environmental toxins and medications. Variations in these genes may impair detoxification, increasing the risk of migraines triggered by chemicals, alcohol, or medication overuse.

    • Nutritional support: Supporting liver health with cruciferous vegetables, antioxidants, and adequate hydration can enhance detoxification.

  4. Glutathione Pathway Genes:

    • Glutathione is a powerful antioxidant that protects the brain from oxidative stress. Genetic variants in glutathione production or recycling can increase inflammation and oxidative damage, contributing to migraines.

    • Nutritional support: Foods rich in sulphur (garlic, onions, broccoli) and supplements like NAC (N-acetyl cysteine) or liposomal glutathione can boost antioxidant defences.

  5. Serotonin Pathway Genes:

    • Genetic variations affecting serotonin production or receptor activity may contribute to migraines, as serotonin plays a key role in vascular tone and pain regulation.

    • Nutritional support: Tryptophan-rich foods (e.g., turkey, eggs, and nuts) and co-factors like vitamin B6 and magnesium can enhance serotonin synthesis.


The Role of Nutrigenomics in Vestibular Migraines

For those with vestibular migraines, nutrigenomics can provide insights into genetic factors influencing the vestibular system, balance, and brain sensitivity. By tailoring dietary and lifestyle interventions to your genetic profile, it’s possible to reduce the frequency and intensity of symptoms like dizziness, vertigo, and nausea.


How I Use Nutrigenomics to Help Manage Migraines

As part of my naturopathic nutritional therapy practice, I offer personalised nutrigenomic testing to identify genetic variations that may be influencing your migraines. This allows us to create a tailored plan that addresses your unique needs.


My Approach:

  1. Genetic Testing:

    • Testing for key SNPs related to migraine pathways, such as MTHFR, COMT, and serotonin regulation.

    • Identifying genetic influences on inflammation, detoxification, and oxidative stress.

  2. Personalised Dietary Recommendations:

    • Adjusting macronutrient and micronutrient intake based on genetic predispositions.

    • Incorporating foods that support your genetic pathways, such as methylated B vitamins, magnesium-rich foods, and omega-3 fatty acids.

  3. Supplementation:

    • Recommending targeted supplements to address genetic variations, such as methylfolate, NAC, magnesium glycinate, or omega-3s.

    • Ensuring supplementation is evidence-based and appropriate for your genetic profile.

  4. Lifestyle Modifications:

    • Incorporating stress management techniques, sleep optimisation, and exercise tailored to your genetic needs.

    • Addressing environmental triggers, such as toxins or allergens, to reduce inflammation.

  5. Ongoing Support:

    • Regular reviews to monitor progress, adjust recommendations, and ensure sustainable improvements.


Practical Steps to Support Your Genes Today

Even without genetic testing, there are practical steps you can take to support gene expression and reduce migraine triggers:

  1. Focus on Anti-Inflammatory Foods:

    • Include omega-3-rich foods like salmon, walnuts, and flaxseeds.

    • Add colourful fruits and vegetables high in antioxidants, such as berries, spinach, and sweet potatoes.

  2. Support Detoxification:

    • Stay hydrated and include cruciferous vegetables like broccoli, kale, and cauliflower in your diet.

    • Reduce alcohol and processed foods that burden detoxification pathways.

  3. Prioritise Nutrient-Dense Foods:

    • Incorporate magnesium-rich foods (e.g., leafy greens, almonds) and vitamin B6 sources (e.g., bananas, chickpeas).

  4. Track Symptoms:

    • Keep a migraine diary to identify potential genetic triggers and monitor how dietary changes affect your symptoms.


How I Can Help You with Nutrigenomics and Migraine Management

If you’re struggling with migraines or vestibular migraines, understanding your genetic profile can unlock a new level of personalised care. Through my 1-2-1 consultations or Migraine Management Programme, I offer:

  • Nutrigenomic testing to identify key genetic influences.

  • A tailored plan based on your unique genetic, dietary, and lifestyle needs.

  • Ongoing support to optimise your health and reduce your migraine symptoms.

Alternatively, my Migraine Management Course provides a self-paced approach to understanding the root causes of migraines, including insights into nutrigenomics and practical strategies to manage symptoms.


Book Your Free Discovery Call Today

Nutrigenomics offers a powerful, personalised way to address the root causes of migraines and vestibular migraines. Take the first step by booking a free discovery call to learn how I can help you use nutrigenomics to optimise your diet and lifestyle for better health and fewer migraines.



nutritionist, naturopathic nutritionist

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